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Rick Stewart didn't know about the laburnum trees growing in Bulgaria and their prospective to produce a drug for giving up smoking back when he was the primary executive of the pharmaceutical business Amarin. He was too deep inside the drug industry, a location often slammed for its short-sighted concentrate on profits.

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Just then might he identify the chance in those yellow-flowering trees. Now, with the aid of the National Institutes of Health, Stewart is trying to present the laburnum-derived drug to the U.S. market. The pill works by disrupting tobacco yearnings, similar to Pfizer's top-selling Chantix, but potentially without that drug's prominent negative effects and at a much lower rate.

Today, scientists are thrilled about what could be the first new treatment for smoking cigarettes cessation to emerge in years. "We need this," stated David Shurtleff, deputy director of the NIH Center for Complementary and Integrative Health, explaining why his firm is assisting to get the drug approved. But laburnum's guarantee is not new.

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From left, Ronald Martell, Rick Stewart and Anthony Clarke of Extab. Stewart wishes to rebrand the smoking-cessation drug Tabex as Extab for sale in Western European and U.S. markets. (Tom Pilston) In 2007, Stewart had staked his task as the head of Amarin on a different drug. Miraxion was for treating Huntington's Disease, and early on it showed signs of improving symptoms of the neurological disorder.

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Financiers in Amarin, a $240 million business based in New Jersey, were stunned. The business's stock fell 80 percent. Stewart was out of a task. "The CEO always falls on his sword," Stewart, 56, states now. But Miraxion did appear to help patients with Huntington's it simply took longer than the six months allotted during the scientific trials.

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This led Stewart and Anthony Clarke, who likewise lost his job after running the trials for Amarin, to wonder what other misinterpreted drugs were out there. They went on a hunt. "These drugs are uncared for or undesirable. They require tlc," Stewart states. "And pharma, for whatever factor, can't be troubled with them." They set up a small business outside London called Ricanto a mash-up of their very first names.